臨床基盤分野：業績 (2002〜2006年)
Umeda K, Heike T, Nakata-Hizume M, Niwa A, Arai M, Shinoda G, Ma F, Suemori
H, Luo HY, Chui DH, Torii R, Shibuya M, Nakatsuji N, Nakahata T.
Sequential analysis of alpha- and beta-globin gene expression during
erythropoietic differentiation from primate embryonic stem cells.
Stem Cells. Dec;24(12):2627-36 (2006).
Suemori H.
Establishment and therapeutic use of human embryonic stem cell lines.
Hum Cell. May;19(2):65-70 (2006). Review.
Keiko Adachi, Eihachiro Kawase, Kentaro Yasuchika, Tomoyuki
Sumi, Norio Nakatsuji and Hirofumi Suemori.
Establishment of the Gene-Inducible System in Primate Embryonic
Stem Cell Lines.
Stem Cells.Nov;24(11):2566-72 (2006).
Shin-ya Yasuda, Norihiro Tsuneyoshi, Tomoyuki Sumi, Kouichi Hasegawa, Takashi
Tada, Norio Nakatsuji and Hirofumi Suemori.
NANOG maintains self-renewal of primate ES cells in the absence of a feed 笠er
layer.
Genes to Cells. Sep;11(9):1115-23 (2006).
A method for the selection of human embryonic stem cell sub-lines with high cloning efficiency.
Stem Cells, Dec;24(12):2649-60 (2006).
Yasuko Fujimoto, Kouich Hasegawa, Hirofumi Suemori, Juichi Ito and Norio Nakatsuji.
Molecular Cloning and Function of Cynomolgus Monkey Oct-3 Isoforms in Primate
Embryonic Stem Cells.
Stem Cells and Development. Aug;15(4):566-74 (2006).
Hirofumi Suemori, Kentaro Yasuchika, Kouichi Hasegawa, Tsuyoshi Fujioka, Norihiro
Tsuneyoshi and Norio Nakatsuji.
Efficient establishment of human embryonic stem cell lines and long term
maintenance with stable karyotype by enzymatic bulk passage.
Biochemical and Biophysical Research Communications, 345, 926-32 (2006).
Kouichi Hasegawa, Shinichiro Chuma, Takashi Tada, Takayuki Sakurai, Masaru
Tamura, Hirofumi Suemori and Norio Nakatsuji.
Testatin transgenic and knockout mice exhibit normal sex-differentiation.
Biochemical and Biophysical Research Communications, 341, 369-375 (2006).
Umeda K, Heike T, Yoshimoto M, Shinoda G, Shiota M, Suemori H, Luo HY, Chui
DH, Torii R, Shibuya M, Nakatsuji N, Nakahata T.
Identification and characterization of hemoangiogenic progenitors during
cynomolgus monkey embryonic stem cell differentiation.
Stem Cells, 24, 1348-1358 (2006).
Sasaki E, Hanazawa K, Kurita R, Akatsuka A, Yoshizaki T, Ishii H, Tanioka Y,
Ohnishi Y, Suemizu H, Sugawara A, Tamaoki N, Izawa K, Nakazaki Y, Hamada H,
Suemori H, Asano S, Nakatsuji N, Okano H, Tani K.
Establishment of Novel Embryonic Stem Cell Lines Derived from the Common
Marmoset (Callithrix jacchus).
Stem Cells. 23, 1304-1313 (2005).
Ishii T, Yasuchika K, Fujii H, Hoppo T, Baba S, Naito M, Machimoto T, Kamo
N, Suemori H, Nakatsuj 笠i N, Ikai I.
In vitro differentiation and maturation of mouse embryonic stem cells into
hepatocytes.
Experimental Cell Research 309:68-77 (2005).
Hatano SY, Tada M, Kimura H, Yamaguchi S, Kono T, Nakano T, Suemori H, Nakatsuji
N, Tada T.
Pluripotential competence of cells associated with Nanog activity.
Mech. Dev., 122, 67-79, (2005).
Yasushi Takagi, Jun Takahashi, Hidemoto Saiki, Asuka Morizane, Takuya Hayashi,
Yo Kishi, Hitoshi Fukuda, Yo Okamoto, Masaomi Koyanagi, Makoto Ideguchi, Hideki
Hayashi, Takayuki Imazato, Hiroshi Kawasaki, Hirofumi Suemori, Shigeki Omachi,
Hidehiko Iida, Nobuyuki Itoh, Norio Nakatsuji, Yoshiki Sasai and Nobuo Hashimoto.
Dopaminergic neurons generated from monkey embryonic stem cells function
in a Parkinson primate model.
J. Clinic. Invest., 115: 102-109, (2005).
Takao Kuroda, Masako Tada, Hiroshi Kubota, Hironobu Kimura, Shin-ya Hatano,
Hirofumi Suemori, Norio Nakatsuji and Takashi Tada.
Octamer and Sox elements are required for transcriptional cis-regulation
of Nanog gene expression.
Mol. Cell. Biol. 25: 2475-2485 (2005).
Tsuyoshi Fujioka, Kentaro Yasuchika, Yukio Nakamura, Norio Nakatsuji, Hirofumi
Suemori.
A simple and efficient cryopreservation method for primate embryonic stem
cells.
Int. J. Dev. Biol. 48: 1149-1154 (2004).
Tomoyuki Sumi, Yasuko Fujimoto, Norio Nakatsuji, and Hirofumi Suemori.
STAT3 is Dispensable for Maintenance of Self-Renewal in Nonhuman Primate
Embryonic Stem Cells.
Stem Cells, 22, 861-872 (2004)
Umeda K, Heike T, Yoshimoto M, Shiota M, Suemori H, Luo HY, Chui DH, Torii
R, Shibuya M, Nakatsuji N, Nakahata T.
Development of primitive and definitive hematopoiesis from nonhuman primate
embryonic stem cells in vitro.
Development 131,1869-1879 (2004).
Masatoshi Haruta, Yoshiki Sasai, Hiroshi Kawasaki, Kaori Amemiya, Sotaro Ooto,
Masaaki Kitada, Hiro 笠fumi Suemori, Norio Nakatsuji, Chizuka Ide, Yoshihito Honda,
and Masayo Takahashi.
In vitro and in vivo Characterization of Pigment Epithelial Cells Differentiated
from Primate Embryonic Stem Cells.
Invest. Ophth. Vis. Sci. 45, 1020-1025 (2004).
Masataka Furuya, Kentaro Yasuchika, , Yasunori Yoshimura, Norio Nakatsuji and
Hirofumi Suemori.
Electroporation of cynomolgus monkey embryonic stem cells.
Genesis, 37, 180-187 (2003).
Kenji Mizuseki, Tatsunori Sakamoto, Kiichi Watanabe, Keiko Muguruma, Makoto
Ikeya, Ayaka Nishiyama, Akiko Arakawa, Hirofumi Suemori, Norio Nakatsuji , Hiroshi
Kawasaki, Fujio Murakami, and Yoshiki Sasai.
Generation of neural crest-derived peripheral neurons and floor plate cells
from mouse and primate embryonic stem cells.
Proc. Nat. Acad. Sci. USA, 100, 5828-5833 (2003)
Mihoko Nagata, Masafumi Takahasi, Shin-ich Marumatsu, Yasuji Ueda, Yutaka Hanazono,
KoichiTakeuchi,Koji Okada, Yutaka Suzuki, Yasushi Kondo, Hirofumi Suemori, Uichi
Ikeda, Imaharu Nakano, Eiji Kobayashi, Mamoru Hasegawa, Keiya Ozawa, Norio Nakatsuji,
and Kazuyuki Shimada.
Efficient gene transfer of simian immunodeficiency viral vector into cardiomyocytes
derived from primate embryonic stem cell.
J. Gene Med, 5, 921-928 (2003).
Asano, T., Hanazono, Y., Ueda, Y., Muramatsu, S., Kume A., Suemori, H., Suzuki,
Y., Kondo, Y., Harii, K., Hasegawa, M., Nakatsuji, N., and Ozawa, K.
Highly Efficient Gene Transfer into Primate Embryonic Stem Cells with a simian
Lentivirus Vector.
Mol. Therapy, 6, 162-168 (2002).
【著書】
Hirofumi Suemori, Yoshiki Sasai, Katsutsugu Umeda and Norio Nakatsuji.
ES cell lines from the cynomolgus monkey (Macaca fascicularis).
in "Embryonic Stem Cells, A Practical Approach" (Oxford University
Press, NY, USA) 2006
Hirofumi Suemori and Norio Nakatsuji.
Growth and differentiation of cynomolgus ES 笠cells.
in Methods in Enzymologist Vol. 365 (Ed. Wassarman, P. M.), 419-429 (2003)